1.教育状况

2015.09-2019.06 星空体育·中国官方网站动物营养与饲料科学 博士

2012.09-2015.06 星空体育·中国官方网站动物营养与饲料科学 硕士

2008.09-2012.06 星空体育·中国官方网站动物科学 学士

2.工作经历

2019.09-至今：星空体育平台官网，教授，硕士研究生导师/博士研究生导师

代表性论文（第一作者或通讯作者）：

1. Yang, Zhanyi; Li, Tong; Xing, Junya; He, Shiqi; Wu, Wanpeng; Shan, Anshan*; Wang, Jiajun*, The novel peptide adjuvants potentiate antimicrobial properties of melittin against methicillin-resistant Staphylococcus aureus and their efficacy as potential food preservatives. Food Control 2025, 170, 111037.(IF2023=5.6, 中科院1区Top)

2. Gao, Nan; Fang, Cchunyang; Bai, Pengfei; Wang, Jiajun*; Dong, Na; Shan, Anshan*; Zhang, Licong, De novo design of Na+-activated lipopeptides with selective antifungal activity: A promising strategy for antifungal drug discovery. International Journal of Biological Macromolecules. 2024, 283, 137894.(IF2023=7.7, 中科院1区Top)

3. Song Jing, Zhang Shanshan, Xing Junya, Zhang Licong, Wang Jiajun*, Shan Anshan*, Optimizing Therapeutic Efficacy of Antifungal Peptides via Strategic Terminal Amino Acid Modification. Journal of Advanced Research 2024.(IF2023=11.4,中科院1区Top)

4. Nan Gao，Pengfei Bai，Chunyang Fang，Wanpeng Wu，Chongpeng Bi，Jiajun Wang*，Anshan Shan*，Biomimetic Peptide Nanonets: Exploiting Bacterial Entrapment and Macrophage Rerousing for Combatting Infections[J], ACS Nano, 2024，18(37):25446-25464.(IF2023=15.8，中科院1区Top)

5. Yu, Weikang; Guo, Xu; Li, Xue Feng; Wei, Ying Xin; Lyu, Yinfeng; Zhang, Licong; Wang, Jiajun*; Shan, Anshan*, Novel multidomain peptide self-assembly biomaterials based on bola structure and terminal anchoring: Nanotechnology meets antimicrobial therapy. Materials Today Bio 2024, 28. (IF2023=8.7, 中科院分区一区2023Top, 2024-10)

6. Weikang Yu；Xu Guo；Qingrui Li；Xuefeng Li；Yingxin Wei；Changxuan Shao；Licong Zhang；Jiajun Wang*；Anshan Shan*，Revolutionizing Antimicrobial Biomaterials: Integrating an Enzyme Degradation Resistant Sequence into Self-Assembled Nanosystems to Overcome Stability Limitations of Peptide-Based Drugs. Advanced Fiber Materials, 2024, 6 (4), 1188-1211 (IF2023=17.2, 中科院分区一区2023Top, 2024-5)

7. Wu, Wanpeng; Song, Jing; Li, Tong; Li, Wenyu; Wang, Jiajun*; Wang, Shuo; Dong, Na; Shan, Anshan*, Unlocking Antibacterial Potential: Key-Site-Based Regulation of Antibacterial Spectrum of Peptides. Journal of Medicinal Chemistry 2024, 67 (5), 4131-4149. (IF2023=6.8, 中科院分区2023一区Top, 2024-2-29)

8. Gao, Nan; Wang, Jiajun*; Fang, Chunyang; Bai, Pengfei; Sun, Yu; Wu, Wanpeng; Shan, Anshan*. Combating bacterial infections with host defense peptides: Shifting focus from bacteria to host immunity. Drug Resistance Updates, 2023, 72: 10103 (IF2022=24.3, 中科院分区2023一区Top, 2023-12)

9. Su, Yunzhe; Sun, Taotao; Gao, Junhan; Zhang, Chenxu; Liu, Xuesheng; Bi, Chongpeng; Wang, Jiajun*; Shan, Anshan*. Anti-Proteolytic Peptide R7I Protects the Intestinal Barrier and Alleviates Fatty Acid Malabsorption in Salmonella Typhimurium-Infected Mice. International Journal of Molecular Sciences, 2023, 24:22 (IF2022=5.6, 中科院分区2023二区, 2023-11)

10. Yang, Zhanyi; He, Shiqi; Wei, Yingxin; Li, Xuefeng; Shan, Anshan*; Wang, Jiajun*, Antimicrobial peptides in combination with citronellal efficiently kills multidrug resistance bacteria. PHYTOMEDICINE, 2023, 120: 155070 (IF2022=7.9, 中科院分区2023一区Top, 2023-11)

11. He, Shiqi; Yang, Zhanyi; Li, Xuefeng; Wu, Hua; Zhang, Licong; Shan, Anahsn*; Wang, Jiajun*, Boosting Stability and Therapeutic Potential of Proteolysis-Resistant Antimicrobial Peptides by End-Tagging β-Naphthylalanine. Acta Biomaterialia, 2023, 164:175-194. (IF2022=9.7, 中科院分区2023一区Top, 2023-5)

12. Yu, Weikang; Sun, Yu; Li, Wenyu; Guo, Xu.; Liu, Xuesheng; Wu, Wanpeng; Yu, Wanqi; Wang, Jiajun*; Shan, Anshan*, Self-Assembly of Antimicrobial Peptide-Based Micelles Breaks the Limitation of Trypsin. ACS Applied Materials & Interfaces, 2022,15(1):494-510 (IF2021=10.383, 中科院分区2022二区Top, 2022-12)

13. Sun, Taotao; Liu, Xuesheng; Su, Yunzhe; Wang, Zihang; Cheng, Baojing; Dong, Na; Wang, Jiajun*; Shan, Anshan*. The Efficacy of Anti-Proteolytic Peptide R7I in Intestinal Inflammation, Function, Microbiota, and Metabolites by Multi-Omics Analysis in Murine Bacterial Enteritis. Bioengineering & Translational Medicine. 2023, 8 (2). (IF2021=10.684, 中科院分区2022二区, 2022-11-18)

14. He, Shiqi; Yang, Zhanyi; Li, Xuefeng; Wu, Hua; Zhang, Licong; Wang, Jiajun*; Shan, Anshan*, Optimized Proteolytic Resistance Motif (DabW)-Based U1-2WD: A Membrane-Induced Self-Aggregating Peptide to Trigger Bacterial Agglutination and Death. Acta Biomaterialia, 2022, 153, 540-556. (IF2021=10.633, 中科院分区2022一区Top, 2022-11)

15. Wang, Jiajun*; Li, Wenyu; KHosravi-Darani, Kianoush; Kim, In Ho, Editorial: The Development and Utilization of Novel Antibiotic Alternatives. Frontiers in Microbiology, 2022, 13:1008850. (IF2021=6.064, 中科院分区2022二区Top, 2022-8-31)

16. Li, Qiuke; Li, Jinze; Yu, Weikang; Wang, Zhihua; Li, Jiawei, Feng, Xingjun; Wang, Jiajun*; Shan, Anshan*, De Novo Design of A pH-Triggered Self-Assembled β-Hairpin Nanopeptide with the Dual Biological Functions for Antibacterial and Entrapment. Journal of Nanobiotechnology, 2021, 19:183. (IF2020=10.435, 中科院分区2021一区Top, 2021-6-14)

17. Yu, Weikang#; Wang, Jiajun#; Wang, Zihang; Li, Lingxue; Li, Wenyu; Song, Jing; Zhang, Shanshan; Shan, Anshan*, PEGylation of the Antimicrobial Peptide PG-1: A Link between Propensity for Nanostructuring and Capacity of the Antitrypsin Hydrolytic Ability[J]. Journal of Medicinal Chemistry, 2021, 64 (14): 10469-10481. (IF2020=7.446, 中科院分区(升级)2021一区Top. 2021-07)

18. 于伟康,张珊珊,杨占一,王家俊*,单安山*.超分子多肽自组装在生物医学中的应用[J].生物工程学报, 2021, 37 (07):2240-2255.

19. Yang, Yang; Wang, Chenxi; Gao, Nan; Lyu, Yinfeng; Zhang, Licong; Zhang, Sujiang; Wang, Jiajun*; Shan, Anshan*, A Novel Dual-Targeted α-Helical Peptide with Potent Antifungal Activity against Fluconazole-Resistant Candida Albicans Clinical Isolates[J]. Frontiers in Microbiology, 2020, 11 (548620). (IF2019=4.236,中科院分区(升级)2020二区Top, 2020-9-30)

20. He, Shiqi; Yang, Zhanyi; Yu, Weikang; Li, Jiawei; Li, Zhongyu; Wang, Jiajun*; Shan, Anshan*, Systematically Studying the Optimal Amino Acid Distribution Patterns of the Amphiphilic Structure by Using the Ultrashort Amphiphiles[J]. Frontiers in Microbiology, 2020, 11:569118. (IF2019=4.236,中科院分区(升级)2020二区Top, 2020-11-25)

21. Wang, Jiajun; Dou, Xiujing; Song, Jing; Lyu, Yinfeng; Zhu, Xin; Xu, Lin; Li, Weizhong; Shan, Anshan*, Antimicrobial Peptides: Promising Alternatives in the Post Feeding Antibiotic era[J], Medicinal Research Reviews, 2019, 39 (3): 831-859. (IF2018=9.791, 中科院分区(升级)2019一区Top, 热点文章, 2019-05)

22. Song, Jing#; Wang, Jiajun#; Zhan, Na; Sun, Taotao; Yu, Weikang; Zhang, Licong; Shan, Anshan*; Zhang, Aizhong, Therapeutic Potential of Trp-Rich Engineered Amphiphiles by Single Hydrophobic Amino Acid End-Tagging, ACS Applied Materials & Interfaces, 2019, 11 (47): 43820-43834. (IF2018=8.456, 中科院分区(升级)2019一区Top, 2019-11-27)

23. Wang, Jiajun#; Song, Jing#; Yang, Zhanyi; He, Shiqi; Yang, Yi; Feng, Xingjun; Dou, Xiujing; Shan, Anshan*, Antimicrobial Peptides with High Proteolytic Resistance for Combating Gram-Negative Bacteria[J], Journal of Medicinal Chemistry, 2019, 62 (5): 2286-2304. (IF2018=6.054, 中科院分区(升级)2019一区Top,2019-3-14)

24. Chou, Shuli#; Wang, Jiajun#; Shang, Lu; Akhtar Muhammad Usman; Wang, Zhihua; Shi, Baoming; Feng, Xingjun; Shan, Anshan*, Short, Symmetric-Helical Peptides Have Narrow-Spectrum Activity with Low Resistance Potential and High Selectivity[J]. Biomaterials Science, 2019, 7 (6): 2394-2409.(IF2018=5.251, 中科院分区(升级)2019二区, 2019-6-1)

25. Wang, Jiajun#; Chou, Shuli#; Yang, Zhanyi; Yang, Yang; Wang, Zhihua; Song, Jing; Dou, Xiujing; Shan, Anshan*, Combating Drug-Resistant Fungi with Novel Imperfectly Amphipathic Palindromic Peptides[J]. Journal of Medicinal Chemistry, 2018, 61 (9): 3889-3907. (IF2017=6.253, 中科院分区(升级)2018一区,2018-5-10)

26. Wang, Jiajun; Chou, Shuli; Xu, Lin; Zhu, Xin; Dong, Na; Shan, Anshan*; Chen Zhihui, High Specific Selectivity and Membrane-Active Mechanism of the Synthetic Centrosymmetric Alpha-Helical Peptides with Gly-Gly Pairs[J]. Scientific Reports, 2015, 5: 15963. (IF2014=5.578, 中科院分区2015二区,2015-11-4)

在研课题

(1) 黑龙江省人社厅, 黑龙江省博士后面上项目, 脂酰化富脯氨酸肽分子的全新设计、纳米组装体构建及其体内应用效果研究, 主持

(2) 中国博士后基金委, 中国博士后面上项目, 抗酶解型Trp富集肽的分子设计、构效关系及抗菌机制研究, 主持

(3) 黑龙江省人社厅， 黑龙江省博士后特别资助项目，纳米靶向捕获肽分子骨架设计及其对腹泻仔猪肠屏障功能影响的研究，主持

(4) 中国博士后基金委, 中国博士后特别资助项目,抗酶解型靶向捕获肽的分子设计及其对仔猪肠黏膜屏障保护作用的研究,主持

(5) 国家自然科学基金委员会, 面上项目, 基于先天免疫抗菌模式研发的靶向捕获肽对仔猪肠黏膜屏障保护作用的研究，主持

(6) 国家自然科学基金委员会, 青年科学基金项目,高稳定脂酰肽的分子设计、纳米组装体构建及猪肠道内抗菌效力研究，结题，主持

(7) 黑龙江省科技厅, 黑龙江省自然科学基金优秀青年项目, 抗酶解BETA-折叠肽的全新设计及其对腹泻断奶仔猪肠道健康的影响, 结题，主持